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I don't know, no official specs have been announced. In the vids I think they use a gtx580 but that probably is not needed for a decent frame rate. If your current graphics card is sli or crossfire enabled then that route would make more economical sense.
Didn't like how the AI just stood there taking cover when the Player is right in front of them. Also the AI characters keep running in the line of fire, you would they would change their route at minimum. Having said that, I could not care less about the single player mode, I'd really like to see the online gameplay.
there was some dumbass bug in the medal of honor 2010 single player game for pc, totally ruined single player for me, but the multi player kicked ass